These were consecutive patients until 2015 then only those considered unfit for FMC conditioning as per the UKALL 2014 protocol. Methods: First transplant patients between October 2006 and June 2018 were reviewed. We report the outcomes of 31 patients with ALL transplanted using a NMA conditioning without T cell depletion. Use of truly non-myeloablative (NMA) conditioning reduces toxicity in other contexts but outcome data for ALL patients after NMA transplants is lacking. P001 Low treatment related mortality and relapse leading to excellent outcomes after allogeneic transplantation for acute lymphoblastic leukaemia using a non-myeloablative conditioning without T CELL depletion Mary Lynn Savoie 1,2, Jeff K Davies 3,4, Jamie Cavenagh 3,4, Heather Oakervee 4, Jonathan Sive 4, Matthew Smith 4, Deborah Anderson 4, John Gribben 3,4, Bela Wrench 3,4 1 University of Calgary, Calgary, Canada, 2 Tom Baker Cancer Centre, Calgary, Canada, 3 Barts Cancer Institute, Queen Mary University of London, London, United Kingdom, 4 St Bartholomew's Hospital, Barts Health NHS Trust, Barts Cancer Centre, London, United Kingdomīackground: Allogeneic hematopoietic stem cell transplantation is routinely offered to patients with high-risk or advanced ALL in the hopes of improving outcomes.
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